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(2006) Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults, J Clin Endocrinol Metab, 91(3), pp

The bedtime timing matters because the goal is to amplify a pulse that would otherwise occur naturally during deep sleep, not to introduce a daytime pulse that conflicts with normal pituitary rhythms

The injection process is straightforward once you become comfortable with it, and most users report minimal discomfort after the first few administrations

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It mimics endogenous GLP-1 with 94% homology but with extended half-life (~165 hours) due to albumin binding via a C-18 fatty di-acid side chain