This is probably explained by the fact that S-adenosylmethionine (SAM), which is important for many epigenetic processes, is regenerated by methylcobalamin, whereas cyanocobalamin reduces it (as we explored above)
Shameli K, Ahmad MB, Yunus WMZW, Ibrahim NA, Rahman RA, Jokar M: Silver/poly(lactic acid) nanocomposites: preparation, characterization, and antibacterial activity
The formula contains ingredients that are sensitive to oxidation
Bilezikjian, L.-M., Seifert H, Vale W: (1986) Desensitization to growth hormone-releasing factor (GRF) is associated with downregulation of GRF-binding sites
AOD-9604 (Anti-Obesity Drug 9604) is a 16-amino-acid synthetic peptide based on residues 176-191 of the C-terminal region of human growth hormone, with the N-terminal phenylalanine replaced by tyrosine to improve stability