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Efficient GST activity and adequate glutathione are thus important for neutralizing patulin.[ref] Overall, combinations of slower CYP1A2/CYP3A4 alleles with reduced-function GST or UGT variants can leave someone more vulnerable at normal dietary exposure levels, because reactive mycotoxin intermediates may not be cleared efficiently

2) they have a biostimulating effect on their yielding and 3) they increase the resistance of crops to stress (due to a significant increase in the level of polyphenolic compounds)

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Moreover, Gpx4 has been shown recently to modulate ferroptotic cancer cell death, a specific form of cell death characterized by the production of iron-dependent ROS generation (Yang et al., 2014)

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