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Key Points Essential takeaways from this article The Bottom Line The FDA's warning letter to Novo Nordisk documents what plaintiffs' attorneys have alleged for months: that the company's adverse event reporting was systematically inadequate

The real challenge ahead is to deploy multi-omic profiling in well-characterized and sufficiently powered cohorts, enabling the identification of robust biomarker combinations that guide diagnosis, prognosis, and therapeutic response in chronic neurodegenerative diseases

Brains were fixed in 4% paraformaldehyde and preserved in OCT for immunohistochemistry

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