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The SURPASS-2 trial directly compared tirzepatide to semaglutide 1.0 mg in patients with type 2 diabetes, providing the cleanest head-to-head data available

The full benefits of Ozempic, such as improved blood sugar control and more significant weight loss, usually take longer to manifest, often around 8 to 12 weeks of consistent use

HbA1c levels declined steadily in the semaglutide groups until around week 20, after which they plateaued

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These two drugs each have their own advantages, but they also have their own disadvantages