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Also, these pathways play important roles in the proliferation, survival, migration, and invasion of cells

Cell-culture studies use micromolar concentrations on cultured cells

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Research suggests that it may influence lipid metabolism and fat oxidation processes, primarily through pathways involved in lipolysis and energy utilization without directly stimulating growth hormone or IGF-1 activity

Cardiovascular outcomes have been studied in diabetes programs, but long-term cardiovascular and renal effects need continued follow-up through registries and post-marketing safety data