[Ref] Other Very common (10% or more): Pain (35%), flu syndrome (29%), chest pain (15%), accidental injury (12%), asthenia (12%), fever (12%) Common (1% to 10%): Peripheral edema, weight decrease, weight increase Very rare (less than 0.01%): Body odor, International Normalized Ratio (INR) increased [Ref] Local Very common (10% or more): Injection site reaction (38%) [Ref] Musculoskeletal Musculoskeletal side effects, in chronic hemodialysis patients, for levocarnitine (the active ingredient contained in L-Carnitine) in relation to placebo therapy have included asthenia (8% to 12% vs 8%) and leg cramps (4% to 8% vs 13%)
An additional problem with the analysis of data obtained from databases, such as the DNBC, is evident in the systematic review described above
What did the study find
The FDA-approved injection sites for most of these medications include three primary areas: the abdomen, the front of the thighs, and the upper arms (though upper arm injections often require administration by another person)
Strategies vary from launching new brands and products to just repositioning
