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The DAO enzyme is produced in the villi lining the small intestines and is released to metabolize histamine.[ref] Histamine methyltransferase (HMNT) enzyme: The HMNT enzyme works throughout the body, including in the brain, to deactivate and break down histamine created by your cells .[ref] Too much histamine can result in allergy-like symptoms, including the histamine intolerance symptoms listed above

About 80 hours

For example, both can cause fatigue

It is common for patients to be initially diagnosed with other conditions, such as depression, chronic fatigue syndrome and irritable bowel syndrome before receiving their pernicious anaemia diagnosis[20]

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