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Topiramate and phentermine are available combined into a single FDA-approved pill to treat obesity, called phentermine-topiramate ER

A 2016 contemporary meta-analysis of randomized controlled trials of probiotic supplementation found that short-term probiotic consumption decreased intestinal transit time with consistently greater treatment effects in constipated adults, older adults, and with certain probiotic strains.[5] The effect size at the category level is modest, and the heterogeneity across included trials is substantial

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Sermorelin + Tesamorelin Investigated for complementary GHRH analog effects on metabolic and body composition markers