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In a human CEP290 IVS26 knock-in mouse model, EDIT-101 had strong productive editing rates within photoreceptor cells, effectively restored normal splicing of the CEP290 mRNA, and restored the production of the full-length CEP290 protein [63]

Excellent tolerance with minimal side effects doesn't justify accelerating the escalation schedule

Enhanced autophagic activity may contribute to the preservation of neuronal function by improving cholinergic signaling and reducing oxidative stress accumulation

Carbon dots as versatile nanoarchitectures for the treatment of neurological disorders and their theranostic applications: a review

Matrine induces ferroptosis in cervical cancer through activation of piezo1 channel