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The secondary objective was to investigate the effect of duloxetine on serum BDNF in FM patients and assess the direction of BDNF changes relation to clinical parameters alterations
40 Nevertheless, accumulating evidence indicates that CR is detrimental to skeletal metabolism, as evidenced by reductions in BMD and bone mineral content (BMC), diminished bone formation indices (e.g., bone formation rate, osteoblast number), and a concomitant increase in bone resorption
Its key ingredient, kojic acid, may help reduce the appearance of dark spots, hyperpigmentation and uneven skin tone, supporting a clearer and more radiant complexion
Glucagon-like peptide-1 receptor agonists reduce appetite, slow gastric emptying, enhance glucose-dependent insulin secretion, and improve glycemic control
Time to onset (TTO) was defined as the interval between the date of AE onset (EVENT_DT in the DEMO file) and the date of the start of drug use (START_DT in the THER file)
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