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Permpoon, U
To test the effects of GHK and GHK-PEG on SH-SY5Yneuroblastomacell proliferation, cells were plated in 24 well plates and treated with GHK or PEGylated GHK at 10 and 20 nM for 24 hours and the effect of each treatment on cell proliferation was assessed using a hemocytometer
This stabilizes the free radicals and prevents them from damaging cells
In the db/db mouse model, inhibiting MAP4K4 or mutating the C644 site of Drp1 mitigates cardiac microvascular injury and cardiac dysfunction, highlighting MAP4K4 and SNO-Drp1 as potential therapeutic targets for DCM[194]
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