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A study in 154 pregnant women at increased risk of preeclampsia found that those who were riboflavin deficient were 4.7 times more likely to develop preeclampsia than those who had adequate riboflavin nutritional status (26)

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Nrf2 displays both pro- and anti-atherogenic effects in experimental animal models, and the Nrf2 pathway becomes a promising target for atherosclerosis prevention (234)