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Retatrutides durability data beyond the 18-month Phase 3 window is not yet fully characterised

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Over 68 weeks, participants lost an average of 15 pounds of muscle and 23 pounds of fat

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In 2014, Yang et al

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This combined activity has made it a valuable subject in preclinical research focused on receptor signalling, glucose-related pathways, lipid metabolism, energy expenditure, and broader metabolic regulation

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Still, significant changes can happen over several months

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