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There are several different drugs within the GLP-1 class, including liraglutide, semaglutide, and dulaglutide

By clearing out senescent cells, FOXO4 has the potential to reverse signs of aging at the cellular level, improve tissue function, and reduce the burden of age-related diseases

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The alterations in the overall structure also enhance its affinity to the GLP-1 receptors that are necessary to investigate glucose regulation, insulin signaling, and the pathways related to appetite

Nature Medicine, 29(11), 29092918