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N Engl J Med 364(6):514523 Pavel ME et al (2017) Health-related quality of life for everolimus versus placebo in patients with advanced, non-functional, well-differentiated gastrointestinal or lung neuroendocrine tumours (RADIANT-4): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

18 The treatment protocol for TPE consists of removing and retaining a considerable volume of plasma, approximately 1 to 1.5 plasma volume, 17 and returning the necessary cellular components via a colloid or combination colloid/crystallization solution of either fresh frozen plasma (FFP) or albumin

For IGF-1R/InsR HybridR activation, IGF-1R immunoprecipitates were probed with an antibody against the InsR specific pTyr 1334 residue (#44809G, Invitrogen/ThermoFisher) 52 , and total HybridR determined by immunoblotting with an Anti-InsR antibody (#3025)

Exp Cell Res 232: 435438

The prototypic redox-based signaling mechanism