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Individualizing Treatment Goals While weight reduction is a hallmark of GLP-1 therapy, the ideal target varies: Older adults may need more conservative dosing to prevent frailty Patients with polypharmacy or advanced CKD require closer monitoring Ethnicity, comorbidities and baseline weight all influence treatment strategy Personalization remains essential for balancing efficacy and safety
3) and BRAF-V600E
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Based on these findings, altered metabolism of carnitine/acylcarnitine was observed in AHU, especially in patients with gout who have more changed carnitine/acylcarnitine
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