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This highlights the importance of tailoring interventions to specific pathological contexts, ensuring preservation of beneficial angiogenic responses while mitigating harmful processes (Zlokovic 2011)

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In Australia, lenvatinib/pembrolizumab (PA, 54 TGA working days), acalabrutinib (PA and utilising COR-B, 35 working days), nivolumab/ipilimumab (68 working days), ripretinib (PR, 123 working days) and tucatinib (PR, 113 working days) have been approved under this process by the end of 2020