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Protein concentration was determined by BCA-Assay (ThermoFisher) according to manufacturers instruction
Symptoms associated with riboflavin deficiency include itching and burning eyes, angular stomatitis and cheilosis (cracks and sores in the mouth and lips), bloodshot eyes, glossitis (inflammation of the tongue leading to purplish discoloration), seborrhea (dandruff, flaking skin on scalp and face), trembling, sluggishness, and photophobia (excessive light sensitivity)
Recent research has focused on the metabolic role of the intestine via exploring incretins, such as GLP-1 10,11 , microbiome 12,13 and gut-derived peptides 10,14
Applying patches to skin that is damp, oily, or covered with lotion creates a barrier that prevents proper contact and may lead to premature detachment or inconsistent medication delivery
