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In clinical practice, oral pigmentation discovered incidentally during evaluation for another condition is a well-recognized scenario

A dataset with 1.09 resolution was obtained

The drugs need to be managed in a unique way, using a new strategy that experts have not quite agreed on yet

Upon ligand activation, these nuclear ERs dimerize and translocate to the nucleus where they act as transcription factors by binding to estrogen response elements directly or interact with coactivators such as activator protein 1 or specificity protein 1, to regulate gene expression (19)

Repurposing oncology-specific knowhow and insights regarding antigen selection, platform vector design, regulatory requirements and evolving trial design frameworks has supported movement beyond oncology indications