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If you fall into the slower-responder category, reviewing our detailed guide on why you might not be losing weight on semaglutide can help identify whether something actionable is holding you back or whether you simply need more time at a higher dose
If you have been on a stable dose and suddenly notice your appetite returning stronger than usual, storage-related potency loss could be the cause
Serious but rare side effects include pancreatitis (severe abdominal pain radiating to the back), gallbladder problems (upper right abdominal pain, especially after eating), kidney problems (usually related to severe dehydration), severe allergic reactions (difficulty breathing, severe rash, facial swelling), and vision changes (particularly in people with diabetes)
The combination of a low-FODMAP diet (which many IBS patients already follow) with gradual semaglutide titration tends to produce the best outcomes