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doi: 10.18632/oncotarget.2617 Summary Keywords metformin, glioma, ferroptosis, oxidative stress, AMPK signaling pathway, apoptosis, glioma immunity, CLIC1 Citation Ma X, Sun C, Ding X, Zhang Y, Deng T, Wang Y, Yang H, Ding R, Li H, Wang D and Zheng M (2025) Advances in the treatment of glioma-related signaling pathways and mechanisms by metformin