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Supporting information ACKNOWLEDGMENTS We thank Professor ShiQiang Wang and Assistant Researcher Tingting Hou from the State Key Laboratory of Membrane Biology at Peking University for their valuable guidance and support in experimental design and equipment

Both PAKs and ROCKs are potent regulators of spine morphogenesis and synaptic plasticity

Sermorelin therapy has been used in the past to address conditions such as growth hormone deficiency and age-related decline in growth hormone levels [3]

A Mediterranean diet does not alter plasma trimethylamine N-oxide concentrations in healthy adults at risk for colon cancer

Following physically demanding activities or adventures