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In addition, signs of abusive practices have surfaced in which non-approved indications are masqueraded as approved ones to secure reimbursement or circumvent policy exclusions
Pulmonary The incidence of ICI-induced pulmonary toxicity ranges from 2.7% to 11% for all grades and has a median onset time of 8 to 12 weeks after initiating therapy
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Current evidence quality : Most berberine studies are relatively small, short-term (typically 816 weeks), and conducted primarily in Asian populations, which may limit generalisability
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