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Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons

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Severe Obesity and Established Cardiovascular Disease TRIUMPH-3 (NCT05882045) evaluated 1,949 adults with Class II or Class III obesity (body mass index of at least 35 kg/m) and established cardiovascular disease, with or without type 2 diabetes

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[15] [16] Standard NHS treatment protocols: Without neurological involvement: Hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, then maintenance injections every 2-3 months (lifelong if pernicious anaemia)