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Aim for foods rich in carotenoids, omega-3s, polyphenols, and other antioxidants

Some are in the methylation pathway and others are in the GSH production pathway

It is related to the pKa of the drug and its concentrations by the equation: where, S o = the molar solubility of the undissociated acid (Nic OH ), and S = the molar concentration of the salt form in solution (Nic -ve )

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