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Behavior Illustrative animal behavior on days and weeks after retrobulbar application of L-NAME when mounted on an elevated surface was that rats maintained the initial position of firmly standing on to the surface with posterior legs, almost frozen, with limited movements only (Figure 8, Figure 9)

After 24 h, the mice were euthanized and evaluated for peptide adsorption and penetration analysis by histological examination

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For those exploring nasal spray peptides , this means a 5 mg injectable dose might require 10 to 15 mg when administered nasally