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Semaglutide's activation of GLP-1 receptors may compete with or override nicotine's reinforcing signals, making the addictive stimulus less compelling to the brain's decision-making centers

In REDEFINE and CagriSema research, the drug candidate as monotherapy reached roughly 11.8 percent body-weight reduction

[60] Meachum, C.L., Bernstein, I.L

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