Common Side Effects Most people who take GLP-1 medications experience mild digestive symptoms that often improve over time: Nausea: The most frequently reported side effect Diarrhea: Usually temporary as your body adjusts Stomach upset: Can be reduced by eating smaller meals Loss of appetite: This is actually part of how the medication works Serious but Rare Side Effects Some side effects are uncommon but require immediate medical attention: Thyroid tumors: Reported in less than 1 percent of patients Gallbladder problems: Including gallstones in some patients Severe stomach pain: Could indicate pancreatitis Kidney problems: Especially if you become dehydrated Patients should discuss all potential risks with their healthcare provider before starting any GLP-1 medication

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But it does mean that consistent delivery is arguably more important, because inconsistent absorption could affect the balance of receptor activation
Inject into subcutaneous fat (abdomen or outer thigh), and inject slowly for comfort and improved absorption
This question comes up daily, and there is a lot of misinformation online