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Fatigue may be temporary as the body adapts to new dietary habits and reduced caloric intake

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Based on these mechanisms, several emerging strategies aim to overcome metabolicimmune cooperative resistance and reprogram the tumor microenvironment to enhance immunotherapy efficacy

Clinical implications and practical recommendations In patients with T2DM and established heart failure, SGLT2 inhibitors currently have the strongest evidence base for improving HF outcomes and should be prioritized when not contraindicated [8, 11, 45]

described a surgical technique that allows a smaller flap elevation, the Laurell-Gottlow suturing technique performed before placing the gel and left untied [65]