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choline - alone or in combination with other methyl donors (B12, folate) ameliorates neurological impairment, and is an important constituent of phosphatidylcholine which is a major component of all membranes

Hydroxocobalamin is classified as Pregnancy Category C in the United States, indicating that risk to the fetus cannot be ruled out in the absence of definitive human data

When NAD+ is administered, it is ultimately metabolized to nicotinamide (vitamin B3) as it is utilized in the body

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Folate (vitamin B9) sits at the centre of this process