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Wait, so are we just repurposing diabetes drugs

Instead, we used PPADS (100 M), which did not itself trigger Ca 2+ responses in GLUTag cells or ND neurons (for GLUTag cells mean SEM 340/380 ratio = 0.07 0.02, n = 54

For patients with chronic kidney disease or hepatic impairment, protein targets should be individualised with dietitian input

Intestinal barrier markers of interest included zonulin, diamine oxidase (DAO), histamine, DAO/histamine, lipopolysaccharide (LPS)/immunoglobin A (IgA), LPS/IgG, and LPS/IgM, and these were measured in plasma

For patients who prefer oral over injectable medications Contrave is a tablet taken twice daily, making it a practical alternative for patients who are uncomfortable with or unable to use weekly injections