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By contrast, hesperetin inhibits ferritinophagy and mitigates ferroptosis by modulating the PI3K/AKT/mTOR/ULK1 pathway (100), further underscoring the context-dependent role of ULK1

Reduced glutathione (GSH) is a ubiquitous antioxidant, utilized as a source of reducing equivalents by different GSH peroxidases, which requires constant intracellular GSH synthesis from cysteine, glutamate, and glycine (1, 2)