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The recommendations from the workshop were just published in the medical literature: Recommendations for real-world evidence of efficacy and safety of GLP-1 agonists in Prader-Willi syndrome: Report of a workshop held by the Foundation for Prader-Willi Research and International Prader Willi Syndrome Organisation The experts agreed on the urgent need to collect detailed real-world data from individuals with PWS who are prescribed GLP-1s

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In addition, dual incretin agonists (e.g., GIP/GLP-1 co-agonists such as tirzepatide) have expanded this therapeutic space, while other long-acting or multi-agonist candidates remain investigational ( This review provides a structured overview of how GLP-1 RAs impact gut microbiota composition and function, drawing on recent human clinical studies and mechanistic animal models