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More recently, a small uncontrolled study in five patients with mild-to-moderate AD reported cognitive improvement, measured by the Mini-Mental Status Examination, following supplementation with 300 mg/day of benfotiamine for 18 months (72)

What Reform Would Actually Look Like Effective PBM reform requires addressing four distinct problems: the rebate opacity problem, the spread pricing problem, the vertical integration conflict problem, and the ERISA preemption gap that shields self-insured employer plans from state regulation

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Step-up dosage: After 30 days, the dose is increased to 7 mg once daily