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Psychopharmacology 159 :379-387
Halliwell, B., & Gutteridge, J
In testis, they may be beneficial or even indispensable in the complex process of male germ cells proliferation and maturation, from diploid spermatogonia through meiosis to mature haploid spermatozoa (2)
Indications: CATOVITAL B12 is used in racing pigeons to improve muscle strength and general condition
This occurs when MOR-effector coupling is impaired either by irreversible antagonists or chronic drug treatment presumably because low intrinsic-efficacy agonists such as morphine must occupy a greater fraction of the total receptor population to produce a given level of effect, due to lesser receptor reserve (Christie et al., 1987
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