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The solution should be crystal clear

GLP-1 medications may not be appropriate for patients with certain medical histories, including specific thyroid cancer risks, multiple endocrine neoplasia syndrome type 2, serious allergic reactions to the medication or certain gastrointestinal or pancreatic concerns

Outcomes were tracked from 3 months after the index date to a maximum of 5 years

Of the potential targets discussed earlier, GLP-1 and FGF21 agonists are the best candidates for clinical trials in MetALD, as these agents have the strongest evidence of metabolic benefits and the potential to reduce alcohol use [Table 4]

Tesofensine vs Tesomet Tesomet is tesofensine plus metoprolol, a beta-blocker