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A bifunctional targeted peptide that blocks HER-2 tyrosine kinase and disables mitochondrial function in HER-2-positive carcinoma cells

Once bound, TB-500 promotes actin polymerization into F-actin (filamentous actin), facilitating cell migration, angiogenesis, and extracellular matrix remodeling

When combined with Vitamin C, it helps enhance antioxidant activity while supporting skin vitality and overall wellness

Ladiges, W

In this model, a transwell insert (9321002, cellQART 24-Well Insert 1.0 m pore PET translucent, Northeim, Germany) with a microporous semipermeable membrane was inserted in a 24-well plate and separated the upper (luminal, blood side) and the lower (abluminal, brain side) chambers