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Research Overview# No human data -- All studies described below are preclinical (cell culture or animal models)

However, within the cell, in the cytosol and mitochondria, the GPx system appears to be very efficient in the elimination of H 2 O 2 due to the low (100200 M) K m value of the enzyme [136] and the range of substrates [137]

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precision dosing strategy for phenobarbital in the ICU Occasionally, it may be important to target phenobarbital levels more precisely