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Erratum in: Nat Rev Dis Primers

Lipodystrophy (where the body is unable to produce fat)

Studies show this is because oral tablets are absorbed by the digestive system, causing the medication to be distributed slowly throughout the body, reducing its targeting ability and effectiveness

PLoS One 12:e0178685 Drewe J, Gutmann H, Fricker G, Torok M, Beglinger C, Huwyler J (1999) HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833

Nilotinib is approved under the brand name Tasigna, which is owned and marketed by Novartis, and is indicated for Philadelphia chromosome-positive chronic myeloid leukemia