2.3.4 Epigenetic regulation in the immune-metabolic interactive network In the immune-metabolic interactive regulatory network of PH, epigenetic mechanisms serve as key hubs connecting metabolic abnormalities and immune imbalance through DNA methylation, histone modification, and noncoding RNA regulation
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In summary, current evidence indicates that GLP-1RAs modulate gut microbiota in ways that may underlie their metabolic and organ-protective effects, although heterogeneity between models and trials remains
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Separate research on TRT and Achilles injury risk found a similarly elevated pattern of tendon injury and subsequent surgery in men on testosterone therapy versus matched controls
