With NAFLD affecting 2530% of the global population, up to 6070% of people with type 2 diabetes and almost all individuals with severe obesity [9, 10], an available pharmacotherapy for NAFLD is highly warranted
34 The effect of GLP-1 RA on HF events specifically is less clear, although recent meta-analysis suggested reduced risk of incident HF in people with T2DM without pre-existing HF at baseline
Chen QY, Wang GG, Li W, Jiang YX, Lu XH, Zhou PP
Rotigotine (D2-like agonist) reduced TNF- production and NF- B activation in a mouse model of acute liver injury (Yue et al., 2021), and D2 signaling inhibited NF- B activation by inhibiting Akt in a murine model of acute pancreatitis (Han et al., 2017)
Dermatologically tested with a 0.0 skin irritation index,