Here we determined the rate constants for the individual redox reactions between the two redox-sensitive cysteinyl residues of roGFP2 and the active-site cysteinyl residues of the model class I glutaredoxin PfGrx from the malaria parasite Plasmodium falciparum using stopped-flow kinetic measurements in combination with redox mobility shift assays
Acute and sub-chronic effects of CT-388 treatment on body weight in lean, DIO, and MC4RKO mice We extensively characterized the impact of CT-388 on body weight, food consumption, and food aversion in both acute and sub-chronic settings as well as in normal mice and mouse models of obesity (both diet-induced and genetically induced [MC4RKO] obesity)
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