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It is important to acknowledge that the relationships we found between AC levels, MDD diagnosis, depression severity and depression profiles may be explained to some extent by shared distal environmental and lifestyle factors (e.g., comorbid somatic diseases, sedentary behavior, smoking, high-fat diet, alcohol consumption [61,62,63,64] that could act as confounder or mediators of the association

The lipid-modifying effects should be considered as part of a broader cardiometabolic benefit profile rather than a primary indication for cholesterol management

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In 2026, you can contribute up to $4,400 if you have single coverage or $8,750 for family coverage

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