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[11] Specific disorders [edit] The consequences of neurodegeneration can vary widely depending on the specific region affected, ranging from issues related to movement to the development of dementia

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The observation that the insulinotropic actions of GLP-1 are reduced in type 2 diabetes mellitus (T2DM) led to the development of incretin-based therapies GLP-1 receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors for the treatment of hyperglycaemia in these patients