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[1] [3] This distinguishes semaglutide from some medications that may contribute to dry mouth, such as SGLT2 inhibitors (which can cause dehydration through increased urination) or anticholinergic medications (which directly reduce salivary flow)

The pharmacokinetics of GLP-1 receptor agonists create windows of peak activity, troughs of reduced effect, and transition periods where side effects hit hardest

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Depending on what's flagged, your doctor might order a repeat, increase monitoring, change the dose, or stop the drug entirely