Sex-specific associations with CAD, ischemic stroke, heart failure, and AF were obtained using logistic regression controlling for age, assay array, and 20 principal components
While research indicates that it does not significantly impact growth hormone levels, IGF-1, or glucose metabolism, long-term studies on its safety are still limited
The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for sitagliptin and any potential adverse effects on the breastfed infant from sitagliptin or from the underlying maternal condition
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Here is what to watch for: Exercise intolerance, tiring sooner than usual or refusing to continue walks they previously completed without difficulty Generalised weakness, particularly in the hindquarters Lethargy and reduced engagement with normal activities and play Reduced appetite and progressive weight loss Episodes of fainting or collapse, particularly during or after exertion Breathlessness or laboured breathing, which may become more noticeable with mild activity Abdominal distension in cases where dilated cardiomyopathy has led to fluid accumulation A persistent, soft cough that is more noticeable at rest or at night, which can reflect early fluid in the lungs from cardiac involvement The cardiac signs are among the most significant
