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Dulcolax is generally better reserved for short-term, occasional use because frequent stimulant laxative use can increase the risk of dependency or cramping

"FDA Approves New Drug Treatment for Chronic Weight Management." Link European Medicines Agency (EMA)

This is one reason such options must be approached individually and under medical supervision, since group-level findings never guarantee an individual result

When comparing GLP-1RAs with sulfonylureas or thiazolidinediones, lower risks of intestinal obstruction were observed at one and three years of follow-up, but no associations were observed after five years of follow up

Figure : Glycmie des animaux lors dun test de tolrance au glucose