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When alcohol is present in the body, glutathione is diverted to detoxify it, leaving less available for other critical functions

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Furthermore, bifunctional epoxide hydrolase 2 (log 2 FC = 2.10) involved in detoxication of highly reactive epoxides into less harmful diols, and various xenobiotics was significantly upregulated ( 2 FC = 1.19) which is essential for peroxisome biogenesis, was also upregulated (Supplementary Tables S1, S3, and Figure 5), further highlighting an adaptive peroxisomal response

It also seems to play a role in the elimination of pollutants, drugs and other chemicals