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BPC-157 should ideally be injected subcutaneously near the injury site for maximum localized effect, though it also provides benefits when injected remotely

Mitochondrial ROS production and oxidative mtDNA damage is increased during reoxygenation in the GPX1 knockout mice, in addition to structural abnormalities in cardiac mitochondria and myocytes, suggesting GPX1 may play an important role in protecting cardiac mitochondria from reoxygenation damage in vivo

doi: 10.1038/nature08778

H., & Mori, W